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lmx-igg  (Thermo Fisher)


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    Thermo Fisher lmx-igg
    Lmx Igg, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/lmx-igg/product/Thermo Fisher
    Average 90 stars, based on 1 article reviews
    lmx-igg - by Bioz Stars, 2026-02
    90/100 stars

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    IgA human leukocyte antigen (HLA) class I (A) and class II (B) screening results for the samples from individuals with a different history of alloantigen exposure. Every individual is represented with seven dots (bead groups) for HLA class I and five dots (bead groups) for HLA class II. The arbitrary cut‐off of 500 MFI (represented with dotted line) for any of class I and/or class II bead groups was used to assign samples as IgA‐LMX positive. IgA HLA antibodies were detected mostly against HLA class II in patients with a history of previous transplantation. When IgA HLA antibody signal was compared between the groups with a different history of alloantigen exposure, for both LMX class I and class II bead groups, a significant difference was observed (Kruskal–Wallis test, p < 0.0001). In addition, comparison of MFI signals obtained for IgA HLA antibody within the groups of samples with a history of transplantation and pregnancy (with and without IgG antibody), performed for each LMX class I and class II bead group showed existing significant difference (Mann–Whitney U tests with Bonferroni correction, all p < 0.05)

    Journal: Hla

    Article Title: Low incidence of IgA isotype of HLA antibodies in alloantigen exposed individuals

    doi: 10.1111/tan.14146

    Figure Lengend Snippet: IgA human leukocyte antigen (HLA) class I (A) and class II (B) screening results for the samples from individuals with a different history of alloantigen exposure. Every individual is represented with seven dots (bead groups) for HLA class I and five dots (bead groups) for HLA class II. The arbitrary cut‐off of 500 MFI (represented with dotted line) for any of class I and/or class II bead groups was used to assign samples as IgA‐LMX positive. IgA HLA antibodies were detected mostly against HLA class II in patients with a history of previous transplantation. When IgA HLA antibody signal was compared between the groups with a different history of alloantigen exposure, for both LMX class I and class II bead groups, a significant difference was observed (Kruskal–Wallis test, p < 0.0001). In addition, comparison of MFI signals obtained for IgA HLA antibody within the groups of samples with a history of transplantation and pregnancy (with and without IgG antibody), performed for each LMX class I and class II bead group showed existing significant difference (Mann–Whitney U tests with Bonferroni correction, all p < 0.05)

    Article Snippet: All serum samples were screened for the presence of IgG and IgA isotype of HLA antibodies using Lifecodes Life Screen Deluxe Kit (Immucor) (IgG‐LMX and IgA‐LMX) and further tested with Lifecodes LSA Class I and Class II Kits (Immucor) for IgG and/or IgA following a previously described protocols, when IgA‐LMX positive or necessary.

    Techniques: Transplantation Assay, MANN-WHITNEY